Hermetica Journal
The Ingredient Encyclopedia: what is in your supplements, explained.
Explore ingredient research, product comparisons, and practical routines built around Hermetica's Made-in-USA formulas.
Ishpingo
No clinical trials have been conducted on Ishpingo (Ocotea quixos) for any health outcome in human subjects
Chiric Sanango
The primary clinical dataset consists of 74 case reports analyzed in a 2026 study conducted at the Takiwasi Center, a Peruvian therapeutic rehabili...
Catuaba Bark (Trichilia catigua)
Most research on catuaba bark consists of preclinical animal studies and small human observational trials
Jergon Sacha (Dracontium peruviuanum)
Evidence for Jergon Sacha comes primarily from animal studies rather than human clinical trials
Cordoncillo
No human clinical trials have been conducted on Cordoncillo (Piper spp.) for any indication, including pain relief, inflammation, or parasitic infe...
Matico (Piper aduncum)
Current evidence for matico is limited to in vitro antimicrobial studies and animal inflammation models, with no human clinical trials published
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Amazonian guides
11 published guides.

No clinical trials have been conducted on Ishpingo (Ocotea quixos) for any health outcome in human subjects
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The primary clinical dataset consists of 74 case reports analyzed in a 2026 study conducted at the Takiwasi Center, a Peruvian therapeutic rehabilitation facility specializing in plant-medicine-ass...
Read guide
Catuaba Bark (Trichilia catigua)
Most research on catuaba bark consists of preclinical animal studies and small human observational trials
Read guide
Jergon Sacha (Dracontium peruviuanum)
Evidence for Jergon Sacha comes primarily from animal studies rather than human clinical trials
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No human clinical trials have been conducted on Cordoncillo (Piper spp.) for any indication, including pain relief, inflammation, or parasitic infection
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Current evidence for matico is limited to in vitro antimicrobial studies and animal inflammation models, with no human clinical trials published
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No clinical trials in human subjects have been conducted on Campsiandra comosa or on Huacapurana preparations more broadly, meaning all efficacy inferences are extrapolated from in vitro assays, on...
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Cordoncillo Negro (Piper aduncum)
Current evidence for cordoncillo negro consists primarily of in vitro laboratory studies demonstrating antifungal activity against dermatophyte species and antimicrobial effects against gram-positi...
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Evidence for guaco comes primarily from animal studies and traditional use reports, with no published human clinical trials available
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No randomized controlled trials, observational clinical studies, or pharmacokinetic studies in humans have been conducted on Genipa americana or its isolated constituents as dietary supplements
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No clinical trials have been conducted using Tabernaemontana undulata preparations as the investigational agent; consequently, there are no human-derived effect sizes, confidence intervals, or safe...
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