Zynamite (Mangifera indica Leaf)

Zynamite is a patented extract derived from Mangifera indica (mango) leaves, standardized to contain a minimum of 60% mangiferin (a xanthone C-glucoside polyphenol). Key bioactive compounds include: Mangiferin (primary active compound, ~60-75% concentration in standardized extract), norathyriol (a metabolite of mangiferin produced via gut microbiota), isomangiferin (~2-5%), quercetin (~1-3%), kaempferol (~0.5-1%), and gallic acid (~0.5-1%). Minor xanthones such as homomangiferin and methyl mangiferin are present at trace levels (<0.5%). Macronutrient content is negligible as Zynamite is used in small doses (typically 200-400 mg per serving). Micronutrient contributions are minimal at supplemental doses. Bioavailability notes: Mangiferin has moderate oral bioavailability (~15-25%) due to its hydrophilic nature and molecular size limiting passive absorption; it is primarily metabolized by gut microbiota into norathyriol, which is more lipophilic and bioavailable. Peak plasma concentrations of mangiferin are typically reached within 1-2 hours post-ingestion. Co-administration with food, particularly lipid-containing meals, may modestly enhance absorption. Norathyriol exhibits higher CNS penetration than mangiferin, which may underlie cognitive benefits. The patented Zynamite form claims enhanced standardization and consistency compared to raw mango leaf extracts.