Herbs (Global Traditional) · Native American
Red Root (Ceanothus americanus) (Ceanothus americanus)
Moderate Evidencebotanical
Hermetica Superfood Encyclopedia
Red root (Ceanothus americanus) contains tannins and alkaloids that provide astringent properties traditionally used for lymphatic support. The herb's bioactive compounds work through tissue contraction mechanisms to address bleeding and respiratory congestion.
Red root (Ceanothus americanus) is a deciduous shrub native to eastern and central North America, thriving in dry woodlands, prairies, and sandy soils. The deep red root or root bark is typically harvested and prepared as a decoction, tincture, or extract using water or alcohol to draw out active principles. It belongs to the Rhamnaceae (buckthorn) family and contains cyclic peptide alkaloids, triterpenes, and tannins.
No human clinical trials, RCTs, or meta-analyses were identified in the available sources. Evidence is limited to traditional and anecdotal use without scientific validation. PubMed PMIDs are unavailable due to the absence of clinical research on red root.
Traditional preparations include decoction (1 tsp root per cup water, 1 cup three times daily) or tincture (1:5 in 45% alcohol, 2-3 ml three times daily). No clinically studied dosages or standardized extracts are available as human trials are lacking. Consult a healthcare provider before starting any new supplement.
Red Root (Ceanothus americanus) is a medicinal root/bark preparation, not a significant dietary food source, so macronutrient contributions are negligible at typical therapeutic doses. Key bioactive compounds include: Ceanothine alkaloids (ceanothine B, americine, integerrine) concentrated primarily in root bark at estimated 0.5–1.5% total alkaloid content by dry weight; these are isoquinoline-type alkaloids responsible for much of its pharmacological activity. Tannins (hydrolyzable and condensed) are present at approximately 8–15% dry weight in root bark, contributing to astringent properties; predominant forms include ceanothic acid and related triterpenoid saponins. Flavonoids including rutin and quercetin glycosides are present at low concentrations (estimated 0.3–0.8% dry weight). Triterpene saponins (ceanothic acid, 3-epiceanthic acid) are notable at approximately 2–5% dry weight and are considered primary lymphagogue constituents. Oxalic acid is present and may reduce mineral bioavailability. Mineral content is modest: iron is noted in ethnobotanical literature as a contributing factor to its traditional blood-building reputation, though precise concentrations are not well-documented in modern literature; estimated trace iron at 2–5 mg per 100g dry root. Fiber content is substantial as structural plant material (estimated 20–35% dry weight as cellulose/lignin) but bioavailability is minimal in typical tincture or tea preparations. Chlorogenic acid and caffeic acid derivatives have been identified via HPLC analysis in limited studies. Bioavailability note: most alkaloids and saponins extract readily into both water (tea) and ethanol (tincture); tannins are water-soluble but may bind to alkaloids and reduce net absorption; alcohol-based preparations (1:5, 60% ethanol) are considered most complete extracts for full-spectrum bioactive content.
Red root's tannins exert astringent effects by binding to proteins in mucous membranes and blood vessels, causing tissue contraction. The alkaloids may influence smooth muscle function in respiratory passages, while the herb's compounds potentially support lymphatic drainage through vasoconstrictive actions on lymphatic vessels.
No clinical trials have been conducted on red root (Ceanothus americanus) in humans. The evidence base consists entirely of traditional Native American uses and anecdotal reports. Laboratory studies on the isolated compounds like tannins exist, but specific research on red root's therapeutic effects is absent. Current knowledge relies solely on historical ethnobotanical documentation and traditional preparation methods.
Red root safety profile is poorly documented due to lack of clinical studies. High tannin content may cause gastrointestinal irritation, nausea, or constipation in sensitive individuals. Potential interactions with anticoagulant medications due to astringent properties affecting bleeding. Pregnancy and breastfeeding safety unknown; traditional contraindications include use during pregnancy due to potential uterine effects.
