Herbs (Global Traditional) · European
Quince (Cydonia oblonga) (Cydonia oblonga)
Moderate Evidencebotanical1 PubMed Study
Hermetica Superfood Encyclopedia
Quince (Cydonia oblonga) contains mucilaginous compounds and phenolic acids that provide anti-inflammatory and digestive support properties. The seed mucilage forms protective gels that soothe irritated tissues in both digestive and dermatological applications.
Quince (Cydonia oblonga) is a deciduous tree of the Rosaceae family native to regions from Persia (Iran) to Central Asia, with fruits, leaves, and seeds used medicinally. The plant's active parts include fruit (rich in phenolics), leaves (high in polyphenols), and seeds (mucilage), which are processed through decoctions, aqueous or methanolic extracts, and mucilage extrusion methods.
Human clinical evidence for quince is limited to small preliminary trials without published PMIDs. A small randomized trial in Iran (2018) tested quince seed paste in IBS patients showing 30% symptom reduction, and a Spanish open-label trial found 40% itch reduction in atopic dermatitis with topical seed gel. Most evidence derives from animal, in vitro, or traditional studies rather than robust human trials.
Clinically studied dosages are not standardized. The Iranian IBS trial used quince seed paste (dose unspecified), while the Spanish dermatitis trial applied topical seed gel for 2 weeks (quantity unspecified). No standardized extracts or specific dosage ranges for powder, fruit, or leaf forms are documented in human studies. Consult a healthcare provider before starting any new supplement.
Raw quince fruit (per 100g edible portion): Macronutrients: Carbohydrates 15.3g (primarily fructose 6.3g, glucose 4.3g, sucrose 1.6g), Dietary fiber 1.9g (mix of soluble pectin ~0.5-1.0g and insoluble cellulose), Protein 0.4g, Fat 0.1g, Water 83.8g, Energy 57 kcal. Micronutrients: Vitamin C 15mg (17% DV), Vitamin B6 0.04mg, Folate 3µg, Vitamin E 0.4mg, Potassium 197mg, Copper 0.13mg (14% DV), Iron 0.7mg, Magnesium 8mg, Phosphorus 17mg, Calcium 11mg, Zinc 0.04mg. Bioactive compounds: Polyphenols total ~200-500mg/100g fresh weight (values vary significantly by cultivar and ripeness); Phenolic acids: chlorogenic acid ~20-80mg/100g, 5-caffeoylquinic acid present; Flavonoids: quercetin glycosides ~10-30mg/100g, kaempferol derivatives ~5-15mg/100g, catechins ~5-20mg/100g; Tannins (condensed): ~100-300mg/100g contributing to astringency. Quince seeds (mucilage): Rich in polysaccharides (~16-20% dry weight), primarily xyloglucan and arabinoxylan, responsible for gel-forming properties used in traditional medicine. Bioavailability notes: Quercetin bioavailability from whole fruit is moderate (~25-50% absorption) due to bound glycoside forms requiring colonic hydrolysis; high tannin content may reduce iron absorption when consumed with meals; cooking substantially reduces Vitamin C (losses ~30-50%) but may increase polyphenol extractability; pectin content supports prebiotic effects with moderate fermentability in the colon. Data on exact carotenoid content is limited but beta-carotene and lutein are detected in trace amounts (<50µg/100g).
Quince seeds contain mucilaginous polysaccharides that form protective hydrogels when hydrated, creating barrier effects on mucosal tissues. The phenolic compounds including chlorogenic acid and quercetin derivatives modulate inflammatory pathways by inhibiting NF-κB signaling and reducing pro-inflammatory cytokine production. These mechanisms contribute to both gastrointestinal protection and dermal anti-inflammatory effects.
A small Iranian trial demonstrated that quince seed paste reduced IBS discomfort by 30% compared to baseline, though the study lacked a proper control group. An open-label Spanish study reported 40% reduction in atopic dermatitis-related itching after 2 weeks of topical quince seed gel application. Both studies represent preliminary evidence with limited sample sizes and methodological constraints. No large-scale randomized controlled trials have been conducted to confirm these effects.
Quince fruit is generally safe for consumption, but the seeds contain amygdalin which releases hydrogen cyanide when chewed and should be avoided. Topical quince preparations may cause allergic reactions in sensitive individuals. No significant drug interactions have been reported, though the mucilaginous properties may theoretically affect absorption of oral medications if taken simultaneously. Safety during pregnancy and lactation has not been established through clinical studies.
