Collagen Peptides (Verisol)

Collagen Peptides (Verisol) are bioactive collagen peptides (BCPs) derived from enzymatic hydrolysis of porcine or bovine type I collagen, optimized for skin, hair, and nail benefits. Per typical serving (2.5 g): Protein: ~2.3–2.5 g (predominantly collagen-derived amino acids). Key amino acids per serving: Glycine (~575 mg, ~23%), Proline (~325 mg, ~13%), Hydroxyproline (~300 mg, ~12%), Alanine (~225 mg, ~9%), Glutamic acid (~250 mg, ~10%), Arginine (~200 mg, ~8%). Contains negligible fat (<0.1 g), negligible carbohydrates (<0.1 g), and minimal calories (~9–10 kcal per 2.5 g serving. Molecular weight range: 2–3 kDa (low molecular weight peptides), which confers high oral bioavailability (~90–95% intestinal absorption), significantly superior to intact collagen or gelatin. Bioactive dipeptides and tripeptides include Prolyl-Hydroxyproline (Pro-Hyp) and Hydroxyprolyl-Glycine (Hyp-Gly), which are the primary signaling peptides that stimulate dermal fibroblasts to increase endogenous collagen I, elastin, and proteoglycan synthesis. Mineral content is trace: sodium (~15–30 mg), potassium (<10 mg), calcium (<5 mg), phosphorus (<5 mg) per serving. No significant vitamin, fiber, or lipid content. Free of carbohydrates, sugars, and cholesterol. Verisol is distinct from generic collagen hydrolysates due to its proprietary enzymatic process that enriches specific bioactive peptide fractions targeting skin extracellular matrix receptors. Peak plasma concentration of bioactive dipeptides occurs approximately 1–2 hours post-ingestion. Hydroxyproline-containing peptides persist in plasma for up to 4–6 hours, providing sustained fibroblast stimulation. Not a complete protein source, as it lacks tryptophan and is low in methionine, cysteine, histidine, and tyrosine. Contains no known significant micronutrient cofactors; however, co-supplementation with vitamin C (≥50 mg) is recommended to support endogenous collagen hydroxylation and cross-linking via prolyl hydroxylase enzyme activity.