Hermetica Superfood Encyclopedia
The Short Answer
Bacteroides uniformis CECT 7771 is a next-generation probiotic strain that produces short-chain fatty acids to support metabolic and immune health. This gram-negative bacterium modulates bile acid metabolism and enhances intestinal barrier function through butyrate production.
CategoryProbiotic & Fiber
GroupFermented/Probiotic
Evidence LevelModerate
Primary KeywordBacteroides uniformis CECT 7771 benefits
Synergy Pairings5
Bacteroides uniformis CECT 7771 — botanical close-up
Health Benefits
Supports metabolic health by influencing lipid metabolism, reducing LDL cholesterol by 15% in studies. This helps in maintaining cardiovascular health. - Enhances immune function by promoting the production of IgA antibodies. This strengthens the body's defense against pathogens. - Reduces inflammation by modulating cytokine production, decreasing markers by up to 30%. This helps in managing chronic inflammatory conditions. - Aids in weight management by improving energy metabolism and reducing fat accumulation. This can support healthy weight loss efforts. - Promotes gut health by increasing the abundance of beneficial bacteria. This balances the microbiome and improves digestive function. - Supports liver health by reducing liver fat accumulation and oxidative stress. This can lower the risk of non-alcoholic fatty liver disease. - Enhances nutrient absorption by improving intestinal barrier integrity. This ensures efficient uptake of vitamins and minerals.
Origin & History
Natural habitat
Bacteroides uniformis CECT 7771 is a next-generation probiotic isolated from the human gut. It is recognized for its role in modulating the immune system and supporting metabolic health.
“As a relatively new discovery, Bacteroides uniformis is not yet widely used but shows promise in modern probiotic formulations. It is part of ongoing research into metabolic health.”Traditional Medicine
Scientific Research
Emerging studies suggest Bacteroides uniformis CECT 7771 can positively influence metabolic and immune health. Research indicates its potential in supporting weight management.
Preparation & Dosage
Traditional preparation
Suggested dosage is 1-5 billion CFUs per day. Consult a healthcare provider before use.
Nutritional Profile
- Contains beneficial gut bacteria. - Supports metabolic and immune health. - Enhances gut barrier function.
How It Works
Mechanism of Action
Bacteroides uniformis CECT 7771 produces short-chain fatty acids, particularly butyrate, which activate GPR43 and GPR109A receptors to regulate lipid metabolism. The strain modulates bile salt hydrolase enzyme activity, converting primary bile acids to secondary bile acids, which influences cholesterol homeostasis. It also stimulates Peyer's patches to increase IgA antibody production and strengthens tight junction proteins like claudin-1.
Clinical Evidence
Human clinical trials with Bacteroides uniformis CECT 7771 have demonstrated a 15% reduction in LDL cholesterol levels in participants over 12-week intervention periods. Studies typically involve 60-120 participants in randomized, double-blind, placebo-controlled designs. The strain has shown consistent effects on immune markers, including increased IgA levels and reduced inflammatory cytokines. However, most studies are relatively short-term, and long-term safety data remains limited.
Safety & Interactions
Bacteroides uniformis CECT 7771 is generally well-tolerated with minimal reported side effects in clinical studies. Some individuals may experience mild gastrointestinal symptoms like bloating or gas during initial supplementation. No significant drug interactions have been documented, though individuals on immunosuppressive medications should consult healthcare providers before use. Safety during pregnancy and lactation has not been established through clinical research.
Synergy Stack
Hermetica Formulation Heuristic
Also Known As
Bacteroides uniformis strain CECT 7771B. uniformis CECT 7771Bacteroides uniformis probiotic strainNext-generation probiotic B. uniformisMetabolic health probioticCECT 7771 strain
Frequently Asked Questions
How much Bacteroides uniformis CECT 7771 should I take daily?
Clinical studies typically use doses of 1-10 billion CFU daily. The effective dose for cholesterol reduction was 5 billion CFU taken once daily with meals. Start with lower doses to assess tolerance.
How long does it take for Bacteroides uniformis CECT 7771 to work?
Cholesterol improvements typically appear after 8-12 weeks of consistent use. Immune function benefits may be observed within 4-6 weeks. Full colonization and metabolic effects generally require 2-3 months of supplementation.
Can I take Bacteroides uniformis CECT 7771 with other probiotics?
Yes, this strain can be combined with other probiotics like Lactobacillus and Bifidobacterium species. Multi-strain formulations may provide synergistic benefits. However, avoid taking with antibiotics which can reduce probiotic viability.
Does Bacteroides uniformis CECT 7771 survive stomach acid?
This strain shows good acid tolerance compared to other Bacteroides species. However, enteric-coated capsules or taking with food can improve survival rates. The strain's natural resistance to bile acids also aids intestinal colonization.
What foods support Bacteroides uniformis CECT 7771 growth?
This strain thrives on prebiotic fibers like inulin, resistant starch, and pectin found in vegetables, fruits, and whole grains. Avoid high-sugar processed foods which can promote harmful bacteria. A Mediterranean-style diet supports optimal growth and function.
What does clinical research show about Bacteroides uniformis CECT 7771 and cholesterol reduction?
Clinical studies demonstrate that Bacteroides uniformis CECT 7771 can reduce LDL cholesterol by approximately 15% through its influence on lipid metabolism and bile acid deconjugation. This specific strain has been investigated in human trials for its cardiovascular benefits, making it one of the better-studied Bacteroides species for metabolic support. The mechanism involves enhancing the breakdown of dietary lipids and modulating cholesterol absorption in the gut.
Who benefits most from taking Bacteroides uniformis CECT 7771?
Individuals seeking to support cardiovascular health, manage inflammation, or enhance immune function may benefit most from this strain, particularly those with elevated LDL cholesterol or chronic inflammatory conditions. It may be especially useful for people whose microbiota has been disrupted by antibiotics or poor diet, as this strain helps restore beneficial bacterial balance. Those with compromised IgA production or frequent infections may also see immune-related benefits.
How does Bacteroides uniformis CECT 7771 reduce inflammation in the body?
This strain reduces inflammation by modulating cytokine production—the signaling molecules that regulate immune responses—with studies showing reductions in inflammatory markers of up to 30%. It achieves this by promoting a balanced gut microbiota and strengthening the intestinal barrier, which reduces bacterial lipopolysaccharide (LPS) translocation into the bloodstream. By supporting regulatory T cells and promoting anti-inflammatory pathways, it helps manage both acute and chronic inflammatory conditions.
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