Hermetica Superfood Encyclopedia
The Short Answer
Amaranth seed oil contains exceptionally high levels of squalene (up to 8%) and vitamin E, supporting skin barrier function and cardiovascular health. The oil's omega-6 and omega-9 fatty acids work through anti-inflammatory pathways to reduce oxidative stress and support cellular membrane integrity.
CategoryOil & Fat
GroupOil
Evidence LevelModerate
Primary Keywordamaranth seed oil benefits
Synergy Pairings3

Amaranth Seed Oil — botanical close-up
Health Benefits
Enhances skin hydration, elasticity, and barrier protection with its high squalene content.
Reduces inflammation and supports cardiovascular wellness through omega-6 and omega-9 fatty acids.
Aids in cellular repair and immune modulation with antioxidant-rich vitamin E
Helps lower LDL cholesterol and improve lipid profiles via phytosterols
Provides antimicrobial and healing benefits when applied topically
Supports anti-aging, wound healing, and oxidative balance, making it ideal for integrative skin and body care.
Origin & History

Natural habitat
Native to Central and South America and extracted from the seeds of the Amaranthus plant, Amaranth Seed Oil is a nutrient-dense, golden-hued oil prized for its concentration of squalene, essential fatty acids, and antioxidants. Revered by ancient civilizations such as the Aztecs and Incas, it has evolved into a modern wellness staple for skincare, cardiovascular health, and inflammation reduction.
“Traditionally used by the Aztecs and Incas for its healing, regenerative, and nutritional powers, Amaranth Seed Oil was considered a sacred substance. In modern times, it remains a cornerstone of functional beauty and plant-based wellness practices.”Traditional Medicine
Scientific Research
Research confirms Amaranth Seed Oil’s bioactive composition, particularly its high squalene levels, and demonstrates its potential in skin barrier repair, anti-inflammatory effects, and cardiovascular health support.
Preparation & Dosage

Traditional preparation
Skincare
Use directly on skin or blend into creams and serums for deep hydration and rejuvenation.
Culinary Use
Add as a finishing oil to salads, grains, or steamed vegetables for a nutritional boost.
Supplement
Consume 1 teaspoon daily to support inflammation balance, lipid health, and skin vitality.
Nutritional Profile
- Squalene: A rare antioxidant lipid that moisturizes, protects against oxidative damage, and enhances skin repair.
- Omega-6 and Omega-9 Fatty Acids: Regulate inflammatory responses and support cardiovascular and metabolic health.
- Vitamin E (Tocopherols): Protects skin from environmental stressors and supports immune function.
- Phytosterols: Help reduce cholesterol absorption and improve lipid metabolism.
How It Works
Mechanism of Action
Squalene in amaranth seed oil enhances skin barrier function by increasing ceramide synthesis and reducing transepidermal water loss. The oil's linoleic acid (omega-6) and oleic acid (omega-9) modulate prostaglandin E2 production and nuclear factor-kappa B (NF-κB) signaling pathways, reducing inflammatory cytokine expression. Vitamin E compounds act as chain-breaking antioxidants, protecting cell membranes from lipid peroxidation.
Clinical Evidence
Limited human studies exist specifically for amaranth seed oil supplementation. Small-scale dermatological trials (n=20-40) have shown 15-25% improvements in skin hydration and elasticity after 4-8 weeks of topical application. Animal studies demonstrate cholesterol-lowering effects of 10-20% with daily oral administration, though human cardiovascular data is lacking. Most evidence comes from in vitro studies examining individual compounds rather than whole oil supplementation.
Safety & Interactions
Amaranth seed oil is generally well-tolerated with minimal reported side effects. Topical application may cause mild skin irritation in sensitive individuals. No significant drug interactions have been documented, though the oil's vitamin E content could theoretically enhance anticoagulant medication effects. Safety during pregnancy and lactation has not been established through clinical trials, requiring caution in these populations.
Synergy Stack
Hermetica Formulation Heuristic
Carrier fat (delivery support for lipophilic actives)
Cardio & Circulation | Immune & Inflammation
Also Known As
Amaranthus caudatus oilAmaranthus cruentus oilAmaranthus hypochondriacus oilLove-lies-bleeding oilPrince's feather oilKiwicha oilHuauhtli oilRed cockscomb oil
Frequently Asked Questions
How much squalene is in amaranth seed oil?
Amaranth seed oil contains 6-8% squalene, significantly higher than most other plant oils. This concentration is comparable to shark liver oil but from a sustainable plant source.
Can amaranth seed oil lower cholesterol levels?
Animal studies suggest amaranth seed oil may reduce LDL cholesterol by 10-20% through its omega fatty acid content. However, human clinical trials are needed to confirm these cardiovascular benefits.
What is the recommended dosage for amaranth seed oil?
No standardized dosage exists due to limited clinical research. Topical studies used 2-5% concentrations in skincare formulations, while animal studies used 1-2g daily oral doses.
Does amaranth seed oil help with skin aging?
The high squalene and vitamin E content may support skin elasticity and hydration. Small studies show 15-25% improvement in skin barrier function, though larger trials are needed.
Is amaranth seed oil safe for daily use?
Amaranth seed oil appears safe for regular use with no serious adverse effects reported. However, individuals with seed allergies should exercise caution and perform patch tests before topical use.
Does amaranth seed oil interact with blood-thinning medications like warfarin?
Amaranth seed oil contains vitamin E and omega fatty acids, which have mild anticoagulant properties and may potentiate blood-thinning effects when combined with medications like warfarin or aspirin. Individuals taking anticoagulants should consult their healthcare provider before adding amaranth seed oil supplementation to their regimen. Medical supervision is recommended to monitor clotting times and adjust medication dosages if necessary.
How does amaranth seed oil compare to other plant oils like squalane or jojoba oil for skin hydration?
Amaranth seed oil uniquely combines high squalene content (up to 8%) with vitamin E and phytosterols, making it superior for both hydration and barrier repair compared to jojoba oil, which lacks squalene. Unlike squalane (a hydrogenated derivative), amaranth seed oil provides antioxidant and anti-inflammatory benefits alongside its emollient properties. Squalene in amaranth oil is more bioavailable than in most plant sources, enhancing skin penetration and efficacy.
Who should avoid amaranth seed oil supplementation?
Individuals with seed allergies or sensitivities to Amaranthus species should avoid amaranth seed oil due to cross-reactivity risk. Those taking immunosuppressant medications or with autoimmune conditions should consult a healthcare provider, as amaranth oil's immune-modulating properties may interfere with treatment efficacy. Pregnant and breastfeeding women should seek medical guidance before supplementing, as safety data in these populations remains limited.

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