Vitis vinifera (Sauvignon Blanc)

Vitis vinifera Sauvignon Blanc is a white wine grape containing phenolic acids like caftaric acid and flavanols including catechin and epicatechin. No clinical health benefits have been documented for this cultivar as a supplement, with research focusing primarily on wine chemistry and aroma profiles.

Category: Other Evidence: 2/10 Tier: Preliminary (in-vitro/animal)
Vitis vinifera (Sauvignon Blanc) — Hermetica Encyclopedia

Origin & History

Vitis vinifera (Sauvignon Blanc) is a white grape cultivar originating from Bordeaux, France, now cultivated globally for wine production. The berries are processed into must and fermented into wine, with compounds extracted using methods like SPME-GC-MS for volatiles and HPLC-DAD for phenolics.

Historical & Cultural Context

No historical or traditional medicinal uses of Vitis vinifera (Sauvignon Blanc) are documented in available sources. Modern use is limited to wine production and chemical analysis.

Health Benefits

• No clinical health benefits documented - research focuses solely on wine chemistry and aroma compounds
• Contains phenolic acids like caftaric acid with potential antioxidant properties (no human studies)
• Contains flavanols including (+)-catechin and (-)-epicatechin (no clinical efficacy data)
• Contains flavonols such as quercetin-3-O-glucoside (no biomedical studies available)
• Wine form contains SO₂ with antimicrobial effects (no therapeutic studies)

How It Works

The phenolic acids in Sauvignon Blanc, particularly caftaric acid, theoretically provide antioxidant activity through free radical scavenging mechanisms. Flavanols like (+)-catechin and (-)-epicatechin may modulate cellular oxidative stress pathways, though specific molecular targets remain unstudied in this cultivar.

Scientific Research

No human clinical trials, RCTs, or meta-analyses specific to Vitis vinifera (Sauvignon Blanc) extracts or derivatives were identified. All available research focuses on chemical composition, aroma precursors, and wine properties rather than biomedical applications.

Clinical Summary

No human clinical trials have evaluated Sauvignon Blanc grape extracts for health benefits. Research on this cultivar focuses exclusively on wine production, analyzing chemical composition and aroma compounds for oenological purposes. Unlike other grape varieties, Sauvignon Blanc lacks any documented therapeutic applications or supplement formulations. The absence of clinical data makes it impossible to determine effective dosages or health outcomes.

Nutritional Profile

Sauvignon Blanc grape (Vitis vinifera) nutritional composition per 100g fresh grape berry: Carbohydrates 17-18g (primarily glucose and fructose in roughly equal proportions ~8-9g each), Protein 0.6-0.7g, Fat 0.2g, Fiber 0.9g, Water ~81g. Calories approximately 69-72 kcal/100g. Micronutrients: Vitamin K ~14-22mcg/100g, Vitamin C ~3-4mg/100g (modest), Vitamin B6 ~0.09mg/100g, Potassium ~191mg/100g, Copper ~0.13mg/100g, Manganese ~0.07mg/100g. Bioactive compounds specific to Sauvignon Blanc variety: Phenolic acids including caftaric acid (caffeoyltartaric acid) at ~150-300mg/kg fresh weight, coutaric acid (p-coumaroyltartaric acid) ~50-100mg/kg; Flavanols: (+)-catechin ~20-50mg/kg, (-)-epicatechin ~10-30mg/kg; Flavonols: quercetin-3-O-glucoside ~5-15mg/kg, kaempferol glycosides ~2-8mg/kg; Stilbenes: trans-resveratrol in skin ~0.5-2mg/kg (concentrated in grape skin, minimal in pulp); Varietal thiols (aroma precursors): S-3-(hexan-1-ol)-L-cysteine (3-SH precursor) and S-3-(hexan-1-ol)-glutathione present at trace levels influencing sensory rather than nutritional profile; Tartaric acid ~6-8g/kg and malic acid ~2-4g/kg as dominant organic acids. Carotenoids including beta-carotene ~0.02-0.04mg/100g and lutein ~0.07mg/100g primarily in skin. Bioavailability notes: Phenolic compounds have limited bioavailability from whole grape matrix (~10-30% absorption); quercetin glycosides require gut microbial deglycosylation before absorption; resveratrol bioavailability highly variable (20-50% from grape skin); tartaric acid largely excreted unmetabolized. Most concentration data derived from wine chemistry studies; direct fresh Sauvignon Blanc berry nutritional studies are limited compared to table grape varieties.

Preparation & Dosage

No clinically studied dosage ranges are available, as no human trials on Sauvignon Blanc extracts, powders, or standardized forms have been conducted. Consult a healthcare provider before starting any new supplement.

Synergy & Pairings

Other Vitis vinifera polyphenols, quercetin, catechins, resveratrol, grape seed extract

Safety & Interactions

Safety data for Sauvignon Blanc grape supplements is unavailable due to lack of human studies. Standard grape allergies may apply, with potential reactions including skin irritation or digestive upset. Drug interactions are unknown but theoretically possible given the presence of flavanols that may affect drug metabolism. Pregnant and breastfeeding women should avoid due to insufficient safety data.