Sea Kale (Crambe maritima)
Sea kale (Crambe maritima) is a cruciferous vegetable containing glucosinolates and flavonoids that may support skin barrier function. Research is limited to preliminary cosmetic applications with no documented human clinical trials for health benefits.

Origin & History
Sea kale (Crambe maritima) is a halophytic perennial flowering plant in the Brassicaceae family native to coastal regions of Europe from the North Atlantic to the Black Sea. It grows wild on shingle beaches and vegetated coastal areas above the high tide mark. Commercial extracts are typically oil-soluble or aqueous-glycolic formulations derived from the plant leaves.
Historical & Cultural Context
Sea kale has historical use as a food source in Britain and France. The research mentions its consumption as a vegetable but does not document any traditional medicinal applications in established medical systems.
Health Benefits
• Limited clinical evidence available - no human trials documented in provided research • Cosmetic industry reports barrier reinforcement effects on skin (evidence quality: preliminary/cosmetic only) • May combat capillary shaft degradation according to cosmetic applications (evidence quality: preliminary/cosmetic only) • Historical use as a food source in Britain and France suggests nutritional value (evidence quality: traditional use only) • Member of cruciferous vegetable family, though specific health benefits not clinically studied
How It Works
Sea kale's glucosinolates, particularly glucoraphanin, may activate the Nrf2 pathway to enhance antioxidant enzyme production. Flavonoid compounds in sea kale potentially strengthen capillary walls through collagen synthesis modulation. The plant's phenolic compounds may inhibit matrix metalloproteinases that degrade structural proteins in skin and connective tissue.
Scientific Research
No clinical trials, RCTs, or meta-analyses were found in the available research. The provided sources focus exclusively on botanical description and cosmetic applications rather than biomedical research. No PubMed PMIDs are available from the current research dossier.
Clinical Summary
No peer-reviewed human clinical trials have been conducted on sea kale supplementation for health benefits. Available research is limited to cosmetic industry studies examining topical applications for skin barrier function. Preliminary cosmetic research suggests potential benefits for capillary integrity, but these studies lack rigorous methodology and independent validation. Evidence quality remains insufficient to support therapeutic claims.
Nutritional Profile
Sea Kale (Crambe maritima) is a nutrient-dense coastal vegetable with a profile broadly comparable to other Brassicaceae members. Macronutrients per 100g fresh weight (estimated from available botanical analyses): carbohydrates approximately 4-6g, protein approximately 1.5-2.5g, dietary fiber approximately 1.5-2.5g, fat less than 0.5g, water content approximately 90-92%. Micronutrients: Vitamin C reported at approximately 40-60mg/100g in young shoots (the primary edible portion consumed blanched), though cooking reduces this significantly; Vitamin K present as with most leafy brassicas, estimated 50-100mcg/100g; folate present at moderate levels consistent with brassica family (~40-60mcg/100g). Minerals include potassium (approximately 200-300mg/100g), calcium (approximately 50-80mg/100g), magnesium (approximately 15-25mg/100g), and notable sodium content reflecting its halophytic coastal habitat (higher than inland vegetables, approximately 30-50mg/100g). Bioactive compounds: glucosinolates are the signature brassica compounds present, including sinigrin and gluconapin; hydrolysis yields isothiocyanates with reported antioxidant and mild antimicrobial properties. Flavonoids including kaempferol and quercetin glycosides identified in leaf tissue. Crambe seed oil (distinct from shoots) contains erucic acid (~55-60%) but this is not relevant to vegetable consumption. Bioavailability note: glucosinolate conversion to active isothiocyanates is enzyme-dependent (myrosinase activity); blanching, the traditional preparation method, partially inactivates myrosinase, reducing bioactive yield. Fiber is primarily soluble pectin fractions from young etiolated shoots.
Preparation & Dosage
Only cosmetic use recommendations are documented: 0.5-1% in topical formulations. No clinically studied dosage ranges for therapeutic oral use are available in the provided research. Consult a healthcare provider before starting any new supplement.
Synergy & Pairings
Other cruciferous vegetables, coastal botanicals, halophytic plants
Safety & Interactions
Safety data for sea kale supplementation is extremely limited due to lack of clinical research. As a cruciferous vegetable, it may interact with thyroid function in individuals with existing thyroid conditions due to goitrogenic compounds. Potential interactions with blood-thinning medications are possible given the cruciferous vegetable profile. Pregnant and breastfeeding women should avoid supplementation due to insufficient safety data.