Oxeye Daisy (Leucanthemum vulgare)
Oxeye Daisy (Leucanthemum vulgare) is a European flowering plant traditionally used in folk medicine but lacks clinical evidence for health benefits in humans. The primary concern is its pollen's allergenic proteins that trigger IgE-mediated immune responses in sensitive individuals.

Origin & History
Oxeye Daisy (Leucanthemum vulgare) is a perennial herbaceous plant native to Europe and Asia, now commonly found in North America as an invasive species. It grows readily in temperate grasslands, roadsides, and disturbed areas.
Historical & Cultural Context
No traditional or historical medicinal uses of Oxeye Daisy have been documented in the available research. Its primary mentions are related to its ecological presence and allergenicity.
Health Benefits
• No clinical trials or direct evidence of health benefits for Oxeye Daisy exist in humans. • Pollen allergens from Oxeye Daisy may cause IgE-mediated reactions in allergic individuals. • Limited evidence suggests its pollen supports oocyte maturation in flies, not applicable to humans. • Oxeye Daisy lacks quantified bioactive compounds linked to health benefits. • Allergenic potential noted in 24% of adults with allergic rhinitis.
How It Works
Oxeye Daisy pollen contains allergenic proteins that bind to IgE antibodies on mast cells and basophils, triggering degranulation and histamine release. This mechanism leads to allergic symptoms including rhinitis, conjunctivitis, and potentially more severe reactions in sensitized individuals. No specific bioactive compounds or therapeutic pathways have been clinically validated.
Scientific Research
No human clinical trials, RCTs, or meta-analyses have been identified regarding the medicinal uses of Oxeye Daisy. Studies are limited to allergen sensitization, with no PMIDs providing therapeutic evidence.
Clinical Summary
No randomized controlled trials or systematic clinical studies have evaluated Oxeye Daisy's health effects in humans. The available evidence consists primarily of traditional use documentation and allergenicity studies. Research has focused on identifying pollen as a source of seasonal allergies rather than therapeutic benefits. Current scientific literature does not support any medicinal claims for this plant.
Nutritional Profile
Oxeye Daisy (Leucanthemum vulgare) has extremely limited quantified nutritional data from human dietary studies, as it is rarely consumed as a food ingredient. What IS known from phytochemical analyses: Aerial parts contain sesquiterpene lactones (primarily leucanthemolide and related compounds), flavonoids including luteolin and apigenin glycosides (estimated 0.1–0.5% dry weight based on related Asteraceae species), and phenolic acids such as chlorogenic and caffeic acid derivatives. Essential oil from flowers contains monoterpenes (camphor, borneol) and sesquiterpenes at trace concentrations (<0.1% fresh weight). Leaves and young shoots, occasionally eaten as greens in European folk tradition, likely provide modest crude fiber (estimated 1.5–2.5 g/100 g fresh weight), small amounts of protein (approximately 1–2 g/100 g fresh weight), and micronutrients typical of leafy Asteraceae including calcium, potassium, and magnesium at low-to-moderate levels (no direct assay data published). Pollen contains allergenic proteins (Leu v 1 and related IgE-reactive fractions) identified via immunological studies. Bioavailability of flavonoids is expected to be moderate, consistent with glycosylated forms in related species. No standardized nutritional composition table exists for this species in food databases. All macronutrient and micronutrient figures represent genus/family-level estimations pending direct analytical study.
Preparation & Dosage
There are no clinically studied dosage ranges for Oxeye Daisy extracts, powder, or other forms due to the absence of relevant human trials. Consult a healthcare provider before starting any new supplement.
Synergy & Pairings
N/A
Safety & Interactions
Oxeye Daisy is generally considered safe for most people when encountered environmentally, but individuals with pollen allergies should exercise caution during flowering season. The plant's pollen can trigger allergic rhinitis, asthma, and conjunctivitis in sensitive individuals. No documented drug interactions exist, but pregnant and breastfeeding women should avoid internal use due to lack of safety data. Contact dermatitis may occur in some individuals handling the fresh plant.