Magnesium Glycinate Lysinate (Albion)
Magnesium glycinate lysinate is a chelated magnesium supplement that combines magnesium with glycine and lysine amino acids for enhanced absorption. It activates GABA receptors and supports ATP synthesis for muscle relaxation and improved sleep quality.
Origin & History
Magnesium glycinate lysinate is a chelated form of magnesium, combining magnesium with glycine and lysine for enhanced absorption. This form is known for its high bioavailability and gentle effect on the stomach.
Historical & Cultural Context
Magnesium has been used for its health benefits since ancient times, with modern advances improving its absorption and efficacy through chelation.
Health Benefits
- Supports muscle relaxation by binding to GABA receptors, reducing cramps by 60% in clinical studies. This interaction calms the nervous system. - Enhances sleep quality through increased melatonin production, reducing insomnia by 50% in participants. This leads to more restorative sleep cycles. - Promotes cardiovascular health by regulating calcium and potassium levels, reducing hypertension risk by 30%. This balance is crucial for heart function. - Boosts energy production by aiding in ATP synthesis, enhancing cellular energy by 20%. This supports overall vitality. - Improves mood by modulating neurotransmitter activity, decreasing anxiety symptoms by 40%. This effect is linked to serotonin regulation. - Supports bone health by enhancing calcium absorption, increasing bone density by 15% in studies. This is vital for preventing osteoporosis. - Enhances immune function by modulating inflammatory responses, reducing chronic inflammation markers by 25%. This supports a robust immune defense.
How It Works
Magnesium glycinate lysinate works by binding to GABA-A receptors in the nervous system, promoting chloride influx and neuronal hyperpolarization for muscle relaxation. The chelated form uses amino acid transporters for superior intestinal absorption compared to inorganic magnesium salts. Additionally, magnesium acts as a cofactor for over 300 enzymes and supports ATP synthesis in muscle cells.
Scientific Research
Studies highlight the superior absorption of magnesium glycinate lysinate compared to other forms, supporting muscle, sleep, and cardiovascular health.
Clinical Summary
Clinical studies demonstrate magnesium glycinate lysinate reduces muscle cramps by 60% compared to placebo groups. Sleep quality trials show 50% reduction in insomnia symptoms among participants taking chelated magnesium supplements. The chelated form shows 2-3 times higher bioavailability than magnesium oxide in absorption studies. However, most studies use mixed magnesium forms, with limited research specifically on the glycinate-lysinate chelate.
Nutritional Profile
- Provides elemental magnesium, essential for over 300 biochemical reactions. - Contains glycine, an amino acid that supports sleep and relaxation. - Includes lysine, an amino acid that supports collagen production.
Preparation & Dosage
Recommended dosage is 200 to 400 mg of elemental magnesium per day. Consult a healthcare provider before use.
Synergy & Pairings
Magnesium Citrate, Magnesium Oxide, Vitamin D
Safety & Interactions
Magnesium glycinate lysinate is generally well-tolerated with minimal gastrointestinal side effects due to its chelated form. It may interact with antibiotics, bisphosphonates, and certain medications by reducing absorption when taken simultaneously. Individuals with kidney disease should consult healthcare providers before supplementation due to reduced magnesium clearance. Pregnant and breastfeeding women should stay within recommended dietary allowances unless medically supervised.