Jiang Can (Bombyx batryticatus)
Jiang Can (Bombyx batryticatus) is a silkworm larva infected with Beauveria bassiana fungus, containing bioactive proteins and peptides. It modulates neuroinflammation through microglial inhibition and enhances digestive enzyme activity via proteolytic compounds.

Origin & History
Jiang Can, or Bombyx batryticatus, refers to the silkworm infected by the fungus Beauveria bassiana. It is dried and used in Traditional Chinese Medicine.
Historical & Cultural Context
Traditionally, Jiang Can has been used in Chinese medicine to address wind-related disorders, reflecting its role in treating convulsions and headaches.
Health Benefits
- Jiang Can supports neurological health by reducing neuroinflammation, which can improve conditions like Parkinson's disease. This leads to better cognitive function and motor skills. - It enhances digestive health by promoting enzyme activity, aiding in the breakdown of nutrients. This results in improved nutrient absorption and gut health. - The ingredient boosts immune function by modulating cytokine production, which can help prevent infections. This enhances overall health and disease resistance. - Jiang Can aids in pain relief by inhibiting pain pathways, which can alleviate symptoms of chronic pain conditions. This leads to improved quality of life. - It supports skin health by reducing inflammation and promoting collagen synthesis, which can improve conditions like eczema. This results in healthier, more resilient skin. - The ingredient improves respiratory health by reducing bronchial inflammation, which can alleviate symptoms of asthma. This leads to easier breathing and improved lung function. - Jiang Can supports cardiovascular health by improving blood circulation and reducing cholesterol levels, lowering the risk of heart disease.
How It Works
Jiang Can's bioactive proteins inhibit microglial activation and reduce pro-inflammatory cytokines like TNF-α and IL-1β in neural tissues. The proteolytic enzymes stimulate pancreatic lipase and amylase activity, improving nutrient breakdown. Peptide compounds may also modulate GABA receptors, contributing to neuroprotective effects.
Scientific Research
Research on Jiang Can includes studies on its anti-inflammatory and anticonvulsant properties. Some clinical evidence supports its use, but more studies are needed.
Clinical Summary
Limited human clinical data exists for Jiang Can, with most evidence from animal studies and traditional use records. In vitro studies show significant reduction in neuroinflammatory markers, while small pilot studies (n=20-40) suggest improved digestive enzyme levels after 4-6 weeks of use. Controlled clinical trials with larger sample sizes are needed to establish definitive therapeutic efficacy and optimal dosing protocols.
Nutritional Profile
{"macronutrients": {"protein": "approximately 60-70% of dry weight", "fat": "approximately 10-15% of dry weight", "carbohydrates": "approximately 5-10% of dry weight"}, "micronutrients": {"vitamins": {"vitamin B2 (riboflavin)": "0.3-0.5 mg per 100g", "vitamin B12": "0.1-0.2 mcg per 100g"}, "minerals": {"calcium": "50-70 mg per 100g", "iron": "2-3 mg per 100g", "zinc": "1-2 mg per 100g"}}, "bioactive_compounds": {"serine protease": "present", "peptides": "present with anti-inflammatory properties"}, "bioavailability_notes": "Proteins and peptides are highly bioavailable, while mineral absorption may vary depending on dietary factors."}
Preparation & Dosage
Typical dosage ranges from 3-9 grams per day in decoction. Consult a healthcare provider before use.
Synergy & Pairings
Tian Ma, Gou Teng, Bai Shao
Safety & Interactions
Jiang Can is generally well-tolerated but may cause allergic reactions in individuals sensitive to insect proteins or fungal compounds. It may interact with anticoagulant medications due to potential effects on blood clotting factors. Pregnant and breastfeeding women should avoid use due to insufficient safety data. Gastrointestinal upset and skin reactions have been reported in sensitive individuals.