Dried Buffaloberry
Dried buffaloberry contains high concentrations of anthocyanins, vitamin C, and phenolic compounds that provide potent antioxidant activity. These bioactive compounds work by neutralizing reactive oxygen species and supporting immune function through enhanced white blood cell production.

Origin & History
Buffaloberry is a small, tart fruit native to North America, particularly found in the Great Plains region. It is known for its vibrant red color and high nutritional value.
Historical & Cultural Context
Buffaloberry has been used by Native American tribes for centuries, both as a food source and for its medicinal properties. It is often used in traditional dishes and remedies.
Health Benefits
- Rich in antioxidants, buffaloberry helps protect cells from oxidative damage by neutralizing free radicals and reducing aging signs. - Contains vitamin C, boosting the immune system by enhancing white blood cell activity and reducing illness duration. - High in fiber, buffaloberry supports digestion by promoting bowel regularity and enhancing gut microbiome health. - Provides vitamin E, crucial for skin health, by protecting against UV damage and promoting skin repair. - Contains lycopene, which supports heart health by reducing cholesterol levels and improving blood vessel function. - Offers potassium, helping to maintain electrolyte balance and support cardiovascular health. - Contains flavonoids, which have anti-inflammatory properties, reducing inflammation and supporting joint health.
How It Works
Buffaloberry's anthocyanins and phenolic acids activate the Nrf2 pathway, upregulating antioxidant enzymes like superoxide dismutase and catalase. Vitamin C enhances neutrophil chemotaxis and lymphocyte proliferation while supporting collagen synthesis. The high fiber content promotes beneficial gut bacteria growth and short-chain fatty acid production in the colon.
Scientific Research
Preliminary research indicates buffaloberry's potential in supporting heart health and reducing inflammation. However, more studies are needed to confirm these benefits.
Clinical Summary
Limited clinical research exists specifically on buffaloberry supplementation in humans. Most evidence comes from in vitro studies demonstrating ORAC values of 15,000-20,000 μmol TE/100g, indicating strong antioxidant capacity. Traditional use studies among Indigenous populations suggest digestive and immune benefits, but controlled trials with specific dosages and measured outcomes are lacking. Current evidence is primarily based on nutrient analysis and traditional medicine practices.
Nutritional Profile
- High in antioxidants and polyphenols. - Contains vitamin C and fiber. - Low in calories and fat.
Preparation & Dosage
Consume 10-20 grams of dried buffaloberry daily. Consult a healthcare provider before use.
Synergy & Pairings
Dried Cranberries, Dried Goji Berries, Dried Aronia Berries
Safety & Interactions
Dried buffaloberry is generally recognized as safe when consumed as a food. High doses may cause gastrointestinal upset due to fiber content, particularly in sensitive individuals. No specific drug interactions have been documented, though the vitamin C content may enhance iron absorption. Pregnant and breastfeeding women should consult healthcare providers before supplemental use beyond normal dietary amounts.