Bourbon Red Coffee (Coffea arabica)
Bourbon Red Coffee (Coffea arabica) is a rare heirloom cultivar containing approximately 18.5 mg/g caffeine on a dry weight basis, acting primarily as an adenosine receptor antagonist to promote wakefulness and alertness. Unlike broadly studied coffee varieties, Bourbon Red lacks cultivar-specific clinical trials, so its effects are extrapolated from the general Coffea arabica evidence base.

Origin & History
Bourbon Red Coffee (Coffea arabica) is a premium coffee cultivar grown at high altitudes (1,000-1,800 meters) in volcanic soils, particularly in regions like Rwanda. This variety is characterized by its red cherries when ripe and is known for producing beans with excess glucose, resulting in a smoother, fuller-bodied cup with distinctive caramel and fruit notes.
Historical & Cultural Context
The research dossier provides no information about traditional or historical medicinal use of Bourbon Red Coffee. Sources focus exclusively on agricultural cultivation and flavor profiles rather than therapeutic applications.
Health Benefits
• No clinical health benefits documented in the provided research • Contains 18.5 mg/g caffeine (dry weight basis) - general caffeine effects not clinically studied in this cultivar • No specific therapeutic applications found in the research dossier • No meta-analyses or RCTs available for this specific cultivar • No traditional medicinal uses documented in the sources
How It Works
Caffeine, the primary bioactive in Bourbon Red Coffee at 18.5 mg/g dry weight, competitively antagonizes adenosine A1 and A2A receptors in the central nervous system, inhibiting adenosine-mediated neuronal inhibition and thereby elevating dopamine and norepinephrine signaling. This receptor blockade also inhibits phosphodiesterase enzymes, increasing intracellular cyclic AMP (cAMP) and amplifying adrenergic activity. Chlorogenic acids present in Coffea arabica cultivars additionally inhibit glucose-6-phosphatase and modulate PPAR-gamma pathways, contributing to observed glucose metabolism effects seen in the broader arabica evidence base.
Scientific Research
The research dossier contains no clinical trials, randomized controlled trials, or meta-analyses specific to Bourbon Red Coffee. The only quantitative data provided is the caffeine content of 18.5 mg/g on a dry weight basis, which appears to be from agricultural rather than clinical sources.
Clinical Summary
No randomized controlled trials or meta-analyses have been conducted specifically on the Bourbon Red cultivar of Coffea arabica, making cultivar-specific efficacy claims unsupported by direct clinical evidence. General Coffea arabica research, including large cohort studies of 100,000-plus participants, associates regular coffee consumption with reduced risk of type 2 diabetes and Parkinson's disease, but these findings cannot be attributed exclusively to Bourbon Red. The caffeine content of 18.5 mg/g dry weight aligns with typical arabica ranges, suggesting its acute stimulant pharmacology mirrors that documented in caffeine-specific RCTs showing improved reaction time and reduced perceived fatigue at doses of 3-6 mg/kg body weight. Overall, the evidence strength for Bourbon Red specifically is very low, rated as insufficient by current standards.
Nutritional Profile
Bourbon Red Coffee (Coffea arabica) green bean compositional data based on available coffee science literature: Caffeine: 18.5 mg/g dry weight (confirmed from research dossier) — notably moderate-to-high for an arabica cultivar. Chlorogenic acids (CGAs): estimated 60–120 mg/g dry weight, predominantly 5-caffeoylquinic acid (5-CQA), 3-CQA, and 4-CQA; these are the dominant bioactive polyphenols in arabica green beans and are substantially degraded (40–70% loss) during roasting. Trigonelline: approximately 10–12 mg/g dry weight in green arabica beans; degrades to niacin (vitamin B3) during roasting at rates proportional to roast degree. Sucrose: approximately 60–90 mg/g dry weight in green beans; nearly fully degraded during roasting via Maillard reactions and caramelization. Lipids (coffee oil): approximately 150–170 mg/g dry weight in arabica green beans, rich in diterpenes cafestol and kahweol (bioavailability is filter-dependent — paper filtration removes >90% of diterpenes). Protein: approximately 100–130 mg/g dry weight in green beans; Maillard reaction reduces free amino acid content significantly post-roast. Potassium: approximately 1,600–2,000 mg per 100g dry weight — primary mineral in brewed coffee. Magnesium: approximately 150–200 mg per 100g dry weight. Niacin (B3): formed de novo from trigonelline degradation during roasting; brewed coffee contributes approximately 0.5–1.0 mg per 150 ml cup. Riboflavin (B2): trace levels, approximately 0.01–0.02 mg per 100g green bean. Fiber (as melanoidins in roasted form): 1–3 mg/ml in brewed coffee; melanoidins are high-molecular-weight Maillard products with prebiotic potential. Cultivar-specific compositional data beyond caffeine content (18.5 mg/g) is not independently documented in the provided research dossier; all other values are extrapolated from general Coffea arabica green bean literature and should be considered approximations pending cultivar-specific analysis.
Preparation & Dosage
No clinically studied dosage ranges are available in the research dossier. The only quantitative information is caffeine content at 18.5 mg/g dry weight. No standardized extracts or therapeutic preparations are documented. Consult a healthcare provider before starting any new supplement.
Synergy & Pairings
No synergistic ingredients documented in research
Safety & Interactions
Caffeine from Bourbon Red Coffee can cause dose-dependent side effects including tachycardia, anxiety, insomnia, and elevated blood pressure, particularly at intakes exceeding 400 mg caffeine per day in healthy adults per FDA guidance. It interacts significantly with adenosine-based medications, monoamine oxidase inhibitors (MAOIs), and anticoagulants such as warfarin by altering CYP1A2-mediated hepatic metabolism. Pregnant individuals are advised to limit total caffeine intake to under 200 mg per day due to associations with low birth weight and preterm delivery observed in epidemiological data. Individuals with cardiac arrhythmias, anxiety disorders, or uncontrolled hypertension should consult a physician before regular consumption.